{"title":"TB Treatment with DOT: RCT vs. Effective Program Management","authors":"Phanchai Rattanasuwan","doi":"10.14456/VOL12ISS5PP","DOIUrl":null,"url":null,"abstract":"In the area of Directly-Observed Treatment (DOT), one of 5 essential elements of Directly-Observed Treatment, Short-course (DOTS)- the internationally accepted strategy to combat tuberculosis (TB) promoted by the World Health Organization (WHO) - its usefulness has been continuously debated. Many researchers have tried to conduct randomized controlled trials (RCT) to explore its effectiveness. The results have always led to the conclusion that DOT and self-administration (SA) could produce the same treatment outcomes. However, RCT should be conducted under ideal conditions to develop the efficacy of TB drug regimens, and it may not be necessary for it to be conducted in the field under routine circumstances to find out the effectiveness. Instead of RCT, effective management is needed in the fields, both at program level and at individual level, to produce TB treatment outcomes that come close to the efficacy of TB drug regimens. doi: 10.14456/WJST.2015.70","PeriodicalId":38275,"journal":{"name":"Walailak Journal of Science and Technology","volume":"12 1","pages":"581-585"},"PeriodicalIF":0.0000,"publicationDate":"2015-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"33","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Walailak Journal of Science and Technology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14456/VOL12ISS5PP","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Multidisciplinary","Score":null,"Total":0}
引用次数: 33
Abstract
In the area of Directly-Observed Treatment (DOT), one of 5 essential elements of Directly-Observed Treatment, Short-course (DOTS)- the internationally accepted strategy to combat tuberculosis (TB) promoted by the World Health Organization (WHO) - its usefulness has been continuously debated. Many researchers have tried to conduct randomized controlled trials (RCT) to explore its effectiveness. The results have always led to the conclusion that DOT and self-administration (SA) could produce the same treatment outcomes. However, RCT should be conducted under ideal conditions to develop the efficacy of TB drug regimens, and it may not be necessary for it to be conducted in the field under routine circumstances to find out the effectiveness. Instead of RCT, effective management is needed in the fields, both at program level and at individual level, to produce TB treatment outcomes that come close to the efficacy of TB drug regimens. doi: 10.14456/WJST.2015.70
期刊介绍：
The Walailak Journal of Science and Technology (Walailak J. Sci. & Tech. or WJST), is a peer-reviewed journal covering all areas of science and technology, launched in 2004. It is published 12 Issues (Monthly) by the Institute of Research and Innovation of Walailak University. The scope of the journal includes the following areas of research : - Natural Sciences: Biochemistry, Chemical Engineering, Chemistry, Materials Science, Mathematics, Molecular Biology, Physics and Astronomy. -Life Sciences: Allied Health Sciences, Biomedical Sciences, Dentistry, Genetics, Immunology and Microbiology, Medicine, Neuroscience, Nursing, Pharmaceutics, Psychology, Public Health, Tropical Medicine, Veterinary. -Applied Sciences: Agricultural, Aquaculture, Biotechnology, Computer Science, Cybernetics, Earth and Planetary, Energy, Engineering, Environmental, Food Science, Information Technology, Meat Science, Nanotechnology, Plant Sciences, Systemics
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