Validity of the Risk of Malignancy Index 4 to Preoperative Evaluation of Patients with Adnexal Masses

Ornwitsanate Mongkolmafai, Thumwadee Tangsiriwatthana
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Abstract

Objective: To study the validity of the risk of malignancy index 4 in preoperative prediction for women with adnexal masses. Materials and Methods: A cross-sectional diagnostic study of women with adnexal masses admitted at Khon Kaen Hospital between 18 th May to 31 st July, 2015 for elective surgery. The sensitivity, specificity, positive predictive value and negative predictive value were calculated. Receiver operating characteristic (ROC) curve was used to evaluate the optimal cut-off point for the risk of malignancy index (RMI). Results: One hundred and sixteen women with adnexal masses were recruited (89 cases were benign and 27 cases were malignancy). The optimal cut-off point for RMI 4 in our study was 204 giving the sensitivity 82.8%, specificity 79.3%, positive predictive value 52.3%, and negative predictive value 93.2%. Using a cut-off at 450, sensitivity was 63%, specificity was 86.5%, PPV was 58.6% and NPV was 88.5%. The area under the ROC curve for the RMI 4 was 0.852. Conclusion: The RMI 4 had a validity to discriminate between benign and malignant ovarian tumors.
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恶性肿瘤风险指数4对附件肿物患者术前评估的有效性
目的:探讨恶性肿瘤指数4在女性附件肿物术前预测中的有效性。材料与方法:对2015年5月18日至7月31日在Khon Kaen医院择期手术的女性附件肿块患者进行横断面诊断研究。计算敏感性、特异性、阳性预测值和阴性预测值。采用受试者工作特征(ROC)曲线评价恶性肿瘤风险指数(RMI)的最佳分界点。结果:共收集116例女性附件肿物,其中良性89例,恶性27例。在我们的研究中,RMI 4的最佳分界点为204,灵敏度为82.8%,特异性为79.3%,阳性预测值为52.3%,阴性预测值为93.2%。截止值为450,敏感性为63%,特异性为86.5%,PPV为58.6%,NPV为88.5%。RMI 4的ROC曲线下面积为0.852。结论:RMI - 4具有鉴别卵巢良恶性肿瘤的有效性。
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来源期刊
Thai Journal of Obstetrics and Gynaecology
Thai Journal of Obstetrics and Gynaecology Medicine-Obstetrics and Gynecology
CiteScore
0.40
自引率
0.00%
发文量
3
审稿时长
24 weeks
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