Successful Kidney Transplantation in Patient on Hemodialysis and Intellectual Inferiority

Nikolina Smokovska, J. Masin‐Spasovska, D. Mladenovska, Anastazija Spasovska, G. Spasovski
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Abstract

Abstract Introduction. Kidney transplantation from a living donor is a superior method for treatment of end-stage renal disease (ESRD). The aim of this report is to show that the intellectual inferiority should not be an obstacle for the success of this treatment modality. Case report. We present a 25-year-old female patient with physical and intellectual impairment, with focal-segmental glomerulonephritis diagnosed in 2006 as primary cause of ESRD, regularly followed up at the Department of nephrology. She was initiated on hemodialysis (HD) since July 2014. Although with a bad compliance and hypertension, a good dialysis adequacy was managed with a reduction of the extracellular volume (ECV) and kidney transplantation was indicated as a more convenient treatment option. With psychological assessment of the intellectual inferiority being not contraindication for kidney transplantation and highly motivated family she was transplanted in March 2015. Postoperatively, she was with prolonged hospitalization because of the delayed graft recovery and a couple of perioperative urinary and surgical site infections. In the following months she was slowly adapting to a regular hygienic and diet regimen and intake of medication, with a number of consultations at the Department along with the family. At present, the patient has an excellent health condition and significantly better quality of life. Conclusion. The physical handicap of a moderate degree and mild intellectual impairment are not a contraiidication for treatment of the terminal kidney disease. A successful kidney transplantation reduces the morbidity and mortality from the primary disease, and improve patient’s overall quality of life.
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血液透析和智力低下患者肾移植的成功
摘要介绍。活体肾移植是治疗终末期肾病(ESRD)的一种优越方法。本报告的目的是表明智力低下不应该成为这种治疗方式成功的障碍。病例报告。我们报告了一名25岁的女性患者,她患有身体和智力障碍,2006年诊断为局灶节段性肾小球肾炎,是ESRD的主要原因,并在肾脏病科定期随访。自2014年7月开始血液透析(HD)。尽管依从性差且高血压,但通过减少细胞外体积(ECV)来管理良好的透析充分性,肾移植被认为是更方便的治疗选择。经心理评估,智力低下无肾移植禁忌症,家属积极配合,于2015年3月进行肾移植。术后,由于移植物恢复延迟以及围手术期尿路和手术部位感染,患者住院时间延长。在接下来的几个月里,她慢慢适应了常规的卫生和饮食方案,并与家人一起在该部进行了多次咨询。目前,患者健康状况良好,生活质量明显改善。结论。中度身体残疾和轻度智力障碍不是治疗终末期肾病的禁忌。成功的肾移植可降低原发疾病的发病率和死亡率,提高患者的整体生活质量。
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