Evaluation of periodontal indices in young adults submitted to chlorhexidine 0.12% mouthwash: a randomized clinical trial

Nathale Cruz Batista, Camila Possal de Paula, I. A. V. P. Poiate, Edgard Poiate Junior, E. C. Zuza, G. A. C. G. Camargo
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引用次数: 1

Abstract

Abstract Introduction Gingivitis is a gingival inflammation which can often be treated with oral hygiene such as brushing, flossing, and an antiseptic mouthwash. Objective The aim of this randomized clinical trial was to clinically evaluate the effectiveness of 0.12% chlorhexidine (CHX) solution as an anti-inflammatory agent and for reducing the presence of plaque and inflammation in young adults. Material and method Thirty patients with gingivitis aged 18 to 30 years with a probing depth ≤ 3 mm and a minimum of 20 teeth in the whole mouth were selected and evaluated at baseline and 30 days after treatment. Periodontal clinical parameters were verified: plaque index (PI), gingival index (GI), Simplified Oral Hygiene Index (OHI-S), Simplified Debris Index (DI-S), and Simplified Calculus Index (CI-S) Patients were then randomly allocated into two groups: CHX Group, received chlorhexidine 0.12% labeled as solution 1, and Placebo Group, received saline solution labeled as solution 2. Both groups were included in a hygiene program and received mouthwash. Result Statistically significant differences between CHX and Placebo groups were observed for the variables PI, GI, DI-S, CI-S, and OHI-S (p<0.05 - Paired T Test) after 30 days. The CHX group presented improved GI compared to Placebo at 30 days. Chlorhexidine 0.12% was efficient in the control of periodontium inflammation. Conclusion It can be concluded that chlorhexidine as a mouthwash is efficient in improving periodontal indices in young adults, but it is still controversial whether age can influence GI and OHI-S.
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评价使用0.12%氯己定漱口水的年轻人牙周指数:一项随机临床试验
牙龈炎是一种牙龈炎症,通常可以通过口腔卫生治疗,如刷牙,使用牙线和抗菌漱口水。目的:本随机临床试验的目的是临床评价0.12%氯己定(CHX)溶液作为抗炎剂和减少斑块和炎症存在的有效性。材料与方法选择年龄在18 ~ 30岁、探诊深度≤3mm、全口腔至少20颗牙的牙龈炎患者30例,在治疗前和治疗后30天进行评估。验证牙周临床参数:菌斑指数(PI)、牙龈指数(GI)、简化口腔卫生指数(OHI-S)、简化碎片指数(DI-S)、简化牙石指数(CI-S)。然后将患者随机分为两组:CHX组给予0.12%的洗必定标记为溶液1,安慰剂组给予生理盐水标记为溶液2。两组人都参加了一个卫生项目,并得到了漱口水。结果30 d后,CHX组与安慰剂组PI、GI、DI-S、CI-S、OHI-S指标差异有统计学意义(p<0.05 -配对T检验)。与安慰剂组相比,CHX组在30天的胃肠道改善。0.12%氯己定对牙周炎症有较好的控制作用。结论氯己定漱口水对青壮年牙周指标有改善作用,但年龄对GI和ohi的影响尚存争议。
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审稿时长
15 weeks
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