{"title":"2'-DEOXYCOFORMYCIN AND OTHER ADENOSINE DEAMINASE INHIBITORS","authors":"R. Glazer","doi":"10.1515/DMDI.1980.3.1-2.105","DOIUrl":null,"url":null,"abstract":"A comprehensive review of the pharmacological properties o f adenosine deaminase inhibitors and their interaction with adenosine metabolites and analogs is presented. I have concentrated upon the therapeutic utility o f this class of drugs, rather than upon their mechanism of action with respect to the kinetics o f adenosine deaminase, in the hope that this review will serve as a more useful framework for further drug development in this field, and as a reference for current and future","PeriodicalId":77889,"journal":{"name":"Reviews on drug metabolism and drug interactions","volume":"3 1","pages":"105 - 128"},"PeriodicalIF":0.0000,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/DMDI.1980.3.1-2.105","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Reviews on drug metabolism and drug interactions","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1515/DMDI.1980.3.1-2.105","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
A comprehensive review of the pharmacological properties o f adenosine deaminase inhibitors and their interaction with adenosine metabolites and analogs is presented. I have concentrated upon the therapeutic utility o f this class of drugs, rather than upon their mechanism of action with respect to the kinetics o f adenosine deaminase, in the hope that this review will serve as a more useful framework for further drug development in this field, and as a reference for current and future