{"title":"Role of Epicardial Adipose Tissue in Triggering and Maintaining Atrial Fibrillation","authors":"Ye Tian","doi":"10.15212/cvia.2022.0012","DOIUrl":null,"url":null,"abstract":"Atrial fibrillation is the most common arrhythmia leading to cardiogenic stroke. Without membranous sructure betweenepicardial adipose tissue and atrial myocardium, epicardial adipose tissue directly covers the surface of the atrial myocardium.The formation of an epicardial adipose tissue inflammatory microenvironment, fibrosis, infiltration by epicardialadipose tissue, autonomic dysfunction and oxidative stress are important mechanisms that trigger and maintainatrial fibrillation. Those mechanisms are reviewed herein.","PeriodicalId":41559,"journal":{"name":"Cardiovascular Innovations and Applications","volume":"1 1","pages":""},"PeriodicalIF":0.9000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"3","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cardiovascular Innovations and Applications","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.15212/cvia.2022.0012","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 3
Abstract
Atrial fibrillation is the most common arrhythmia leading to cardiogenic stroke. Without membranous sructure betweenepicardial adipose tissue and atrial myocardium, epicardial adipose tissue directly covers the surface of the atrial myocardium.The formation of an epicardial adipose tissue inflammatory microenvironment, fibrosis, infiltration by epicardialadipose tissue, autonomic dysfunction and oxidative stress are important mechanisms that trigger and maintainatrial fibrillation. Those mechanisms are reviewed herein.