Surgery in Refractory Amiodarone-Induced Thyrotoxicosis

Abstract

Background: Thyroidectomy is a challenging treatment for refractory amiodarone induced thyrotoxicosis (AIT). Objectives: The authors’ aim in this article is to conduct a systematic review of the currently available literature regarding thyroidectomy for the treatment of refractory AIT. Methods: The authors’ systematic review yielded 14 studies encompassing 39 patients. Results: All patients in this study developed thyrotoxicosis on amiodarone especially those with cardiac fragility and benefit from thyroidectomy to control all the symptoms of the hyperthyroid state without surgical risk or consequence on the cardiac status. Conclusion: Thyroidectomy remains the definitive management of refractory AIT and should be instituted sooner rather than later in a patient suffering from this condition. Received: June 18, 2018; Accepted: July 02,2018; Published: July 11,2018 *Corresponding author: Carine Ghassan Richa, Department of Endocrinology, Rafic El Hariri University Hospital, Beirut, Lebanon, Tel: +961 70144157;Email: karine.richa69@gmail.com