New Coronavirus 2 (SARS-CoV-2) Detection Method from Human Nucleic Acid Sequences Using Capsule Networks

IF 1 4区 生物学 Q3 BIOLOGY Brazilian Archives of Biology and Technology Pub Date : 2023-02-13 DOI:10.1590/1678-4324-2023220316
Bihter Das, S. Toraman
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引用次数: 0

Abstract

: The new coronavirus SARS-CoV-2 is an infectious virus with a long incubation period, which was first detected in Wuhan, China, spread all over the world, seriously threatening human life. Therefore, accurate and rapid detection of SARS-CoV-2 is very important for controlling the epidemic and preventing its further spread. Currently, nucleic acid detection makes an important contribution to the prevention and control of SARS-CoV-2. In this study, a new and highly sensitive nucleic acid detection method for SARS-CoV-2 has been proposed. The nucleic acid sequences were digitized by Entropy-based mapping technique. Then, the digitized these sequences were divided into 100-unit sections using the sliding window method and given as input to Capsule Networks.10988 segments (5494 SARS-CoV-2, 5494 normal) are classified with capsule nets. With the proposed method, an accuracy performance of 100% was achieved by using capsule networks to identify SARS-CoV-2 from nucleic acid sequences. The results show that the proposed method successfully identifies SARS-CoV-2 from nucleic acid sequences.
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新型冠状病毒2 (SARS-CoV-2)核酸序列胶囊网络检测方法
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CiteScore
1.80
自引率
0.00%
发文量
116
审稿时长
3 months
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