Mechanism of spironolactone-induced Ca2+ increase in rat testicular arteriole smooth muscle cells revealed by real-time laser scanning confocal microscopy
Yasunori Tamagawa, T. Saino, M. Matsuura, M. Oikawa, Y. Satoh
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引用次数: 1
Abstract
Summary. We reported previously that spironolactone (SPL) induced an increase in intracellular Ca 2+ concentration ([Ca 2+ ]i) in rat testicular arteriole smooth muscle cells. In the present study, we further investigated the mechanism of SPL-induced [Ca 2+ ]i dynamics in rat arteriole smooth muscles. The increase in [Ca 2+ ]i induced by SPL (300 μM) was markedly inhibited in extracellular Ca 2+ -free conditions and in
期刊介绍：
The Archives of Histology and Cytology provides prompt publication in English of original works on the histology and histochemistry of man and animals. The articles published are in principle restricted to studies on vertebrates, but investigations using invertebrates may be accepted when the intention and results present issues of common interest to vertebrate researchers. Pathological studies may also be accepted, if the observations and interpretations are deemed to contribute toward increasing knowledge of the normal features of the cells or tissues concerned. This journal will also publish reviews offering evaluations and critical interpretations of recent studies and theories.
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