Mice models of NAFLD-related HCC

Anna Chen, A. Lu, Jin Yang
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Abstract

Nonalcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC) shows growing tendency across the world, thus requiring the convenient mice models mimic the pathology and pathogenesis of human disease to accelerate the findings of this disease. Herein, we summarized the mice model of NAFLD-HCC recently developed. *Correspondence to: Jin Yang, Translational Medicine Center, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, 310015, China, E-mail: hz_zhiy@163.com
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nafld相关HCC小鼠模型
非酒精性脂肪性肝病(NAFLD)相关的肝细胞癌(HCC)在世界范围内呈增长趋势,因此需要方便的小鼠模型来模拟人类疾病的病理和发病机制,以加速对该疾病的发现。本文对近年来建立的NAFLD-HCC小鼠模型进行综述。*通讯对象:杭州师范大学附属医院转化医学中心杨瑾,浙江杭州310015,E-mail: hz_zhiy@163.com
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