Novel predictive factors of Bell’s Palsy: Neutrophil to lymphocyte ratio and platelet to lymphocyte ratio

A. Pokharel, Jaya Prakash Mayya
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Abstract

Introduction: Inflammation plays an important role in the pathogenesis of Bell’s palsy. Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) are indicators of inflammation. Objectives: The aim of this study was to find the prevalence of Bell's palsy and the mean of neutrophil to lymphocyte ratio and platelet to lymphocyte ratio among them. Methods: This descriptive cross-sectional study was conducted from 1st March 2018 to 1st March 2020 after receiving ethical approval from Institutional Review Committee (Ref. No: 2020-046). Convenience sampling method was used for case selection. Data entry and analysis were done in Statistical Package for the Social Sciences Version 20. Point estimate at 95% confidence interval was calculated along with frequency and proportion for binary data. Result: Out of all patients who visited ENT outpatient department during the study period, the overall prevalence of Bell’s palsy was 0.6% (117) at a 95% confidence interval (0.5-0.72%). Among them, the mean neutrophil to lymphocyte ratio was 5.014 ± 1.63, and the mean platelet to lymphocyte ratio was 207.38 ± 54.59. Conclusion: NLR and PLR can be used as auxiliary param eters in the management of Bell’s palsy. *Correspondence to: Apar Pokharel, College of Medical Sciences, Chitwan, Nepal, Tel: +977-9855058234; E-mail: apar.pokharel@gmail.com
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贝尔氏麻痹的新预测因素:中性粒细胞与淋巴细胞比率和血小板与淋巴细胞比率
炎症在贝尔氏麻痹的发病机制中起着重要的作用。中性粒细胞与淋巴细胞比值(NLR)和血小板与淋巴细胞比值(PLR)是炎症的指标。目的:本研究旨在了解贝尔麻痹的患病率及其中性粒细胞与淋巴细胞比值、血小板与淋巴细胞比值的平均值。方法:本描述性横断面研究在获得机构审查委员会(Ref. No: 2020-046)的伦理批准后,于2018年3月1日至2020年3月1日进行。病例选择采用方便抽样方法。数据输入和分析在统计软件包为社会科学版本20中完成。95%置信区间的点估计与二元数据的频率和比例一起计算。结果:在研究期间访问耳鼻喉科门诊的所有患者中,贝尔麻痹的总体患病率为0.6%(117),95%置信区间(0.5-0.72%)。其中,中性粒细胞与淋巴细胞比值平均值为5.014±1.63,血小板与淋巴细胞比值平均值为207.38±54.59。结论:NLR和PLR可作为贝尔麻痹治疗的辅助参数。*通讯:Apar Pokharel,医学科学院,Chitwan,尼泊尔,电话:+977-9855058234;电子邮件:apar.pokharel@gmail.com
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