Longitudinal imaging studies in schizophrenia: the relationship between brain morphology and outcome measures.

M. Bellani, N. Dusi, P. Brambilla
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引用次数: 14

Abstract

Imaging studies have tried to identify morphological outcome measures of schizophrenia in the last two decades. In particular, longitudinal studies have reported a correlation between larger ventricles, decreased prefrontal volumes and worse outcome. This would potentially allow to isolate subtypes of schizophrenia patients with a worse prognosis and more evident biological impairments, ultimately helping in designing specific rehabilitation interventions.
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精神分裂症的纵向成像研究:脑形态与结果测量之间的关系。
在过去的二十年里,影像学研究试图确定精神分裂症的形态学结果。特别是,纵向研究报告了脑室较大、前额叶体积减小和预后较差之间的相关性。这将有可能分离出预后较差和更明显的生物学损伤的精神分裂症患者亚型,最终有助于设计特定的康复干预措施。
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