COVİD-19 Pnömonisinde Prokalsitonin Düzeylerinin Önemi

Abstract

The importance of procalcitonin Objective: Our aim in this study is to determine how procalcitonin levels are affected in RT-PCR positive COVID-19 pneumonia. To investigate the value of this parameter in terms of biochemical parameters in RT-PCR (Real-Time Polymerase Chain Reaction) positive patients and to propose new opinions on the subject. Method: One hundred COVID-19 patients admitted to the hospital with positive RT-PCR test and above the age of 18 were included in our study. The data of the patients were collected retrospectively from the hospital system. RT-PCR positive patients were divided into two groups as thoracic CT (computed tomography) positive and CT negative, and procalcitonin values were investigated between these two groups. The obtained results were evaluated in the SPSS 25 program. Results: Of the 100 patients with positive RT-PCR tests, 39 patients were CT negative and 61 patients were CT positive. Although the procalcitonin levels measured in the CT positive patient group were higher than the CT negative group, it was not statistically significant (0.113 ± 0.154 ng / mL, 0.064 ± 0.058 ng / mL, p = 0.510). Conclusion: Our results show that the procalcitonin level cannot distinguish the presence of COVID-19 pneumonia in RT-PCR positive patients. High procalcitonin levels may predict that the disease becomes more complicated.