Diyabetik Periferik Nöropati ve Vitamin D İlişkisi

Murat Guntel, Alper Uysal
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Abstract

Relationship Between Diabetic Peripheral Neuropathy and Vitamin D Objective: We aimed to compare electrophysiologically supported and unsupported diabetic peripheral neuropathy (DPN) patients in terms of vitamin D levels within themselves and with the control group. Methods: Patients who applied to Hatay State Hospital Physical Medicine and Rehabilitation Outpatient Clinic and were diagnosed with DPN were divided into two groups according to whether or not pathological findings were detected electrophysiologically. Patients of similar age and gender, who applied to the outpatient clinic with complaints of muscle pain, formed the control group and the groups were compared in terms of vitamin D levels. DPN subgroups were also compared in terms of HbA1c levels and duration of diabetes. Results: No statistically significant difference was found between the DPN groups and the control group in terms of age and gender. Vitamin D levels were found to be significantly higher in the control group compared to the electrophysiologically supported DPN group. When DPN subgroups were compared within themselves, diabetes duration and HbA1c levels were found to be statistically significantly higher in the electrophysiologically supported DPN group. Conclusion: Low vitamin D levels can accelerate the development of neuropathy in diabetic patients and worsen the clinical picture of patients.
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糖尿病外周面与维生素D的关系
糖尿病周围神经病变与维生素D的关系目的:我们旨在比较电生理支持和非电生理支持的糖尿病周围神经病变(DPN)患者自身和对照组的维生素D水平。方法:将到哈塔伊州立医院物理医学与康复门诊就诊并确诊为DPN的患者根据有无电生理病理表现分为两组。年龄、性别相近,以肌肉疼痛为主诉到门诊就诊的患者作为对照组,比较两组患者维生素D水平。DPN亚组也比较了HbA1c水平和糖尿病持续时间。结果:DPN组与对照组在年龄、性别上均无统计学差异。与电生理支持的DPN组相比,对照组的维生素D水平明显更高。当DPN亚组内部比较时,发现电生理支持的DPN组的糖尿病持续时间和HbA1c水平具有统计学意义上的更高。结论:低维生素D水平可加速糖尿病患者神经病变的发展,使患者的临床表现恶化。
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审稿时长
12 weeks
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