Management of anticoagulant treatment in patients who need non-cardiac surgery

C. Rostagno
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Abstract

The periprocedural management of anticoagulation in patients who require non-cardiac surgery is a common clinical problem due to the aging of the population associated with both an increase in the use of anticoagulants and a higher need for surgery. If surgery is needed in a patient on anticoagulant therapy, regardless of the drug used, it is necessary to consider the urgency of the surgical procedure and the balance between the thromboembolic risk related to the discontinuation of therapy and the hemorrhagic risk related to the surgical procedure itself. Finally, a topic still much discussed that derives from the combined evaluation of these factors is the possible indication of a bridge therapy (“bridging anticoagulation”) to limit the thromboembolic risk related to the discontinuation of treatment. The different strategies in patients under antivitamin K and direct oral anticoagulants are reviewed.
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非心脏手术患者抗凝治疗的管理
非心脏手术患者的围手术期抗凝管理是一个常见的临床问题,因为人口老龄化与抗凝剂使用的增加和手术需求的增加有关。如果接受抗凝治疗的患者需要手术,无论使用何种药物,都必须考虑手术的紧迫性,以及与停止治疗相关的血栓栓塞风险和与手术本身相关的出血风险之间的平衡。最后,从这些因素的综合评估中得出的一个仍被广泛讨论的主题是桥接治疗(“桥接抗凝”)的可能适应症,以限制与停止治疗相关的血栓栓塞风险。本文综述了抗维生素K和直接口服抗凝剂治疗患者的不同策略。
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