Advancements in artificial intelligence and machine learning in revolutionising biomarker discovery

IF 0.6 4区 医学 Q4 PHARMACOLOGY & PHARMACY Brazilian Journal of Pharmaceutical Sciences Pub Date : 2023-08-28 DOI:10.1590/s2175-97902023e23146
G. S. Raikar, A. S. Raikar, S. Somnache
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Abstract

The article explores the significance of biomarkers in clinical research and the advantages of utilizing artificial intelligence (AI) and machine learning (ML) in the discovery process. Biomarkers provide a more comprehensive understanding of disease progression and response to therapy compared to traditional indicators. AI and ML offer a new approach to biomarker discovery, leveraging large amounts of data to identify patterns and optimize existing biomarkers. Additionally, the article touches on the emergence of digital biomarkers, which use technology to assess an individual’s physiological and behavioural states, and the importance of properly processing omics and multi-omics data for efficient handling by computer systems. However, the article acknowledges the challenges posed by AI/ML in the identification of biomarkers, including potential biases in the data and the need for diversity in data representation. To address these challenges, the article suggests the importance of regulation and diversity in the development of AI/ML algorithms.
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人工智能和机器学习在彻底改变生物标志物发现方面的进展
本文探讨了生物标志物在临床研究中的意义,以及在发现过程中利用人工智能(AI)和机器学习(ML)的优势。与传统指标相比,生物标志物可以更全面地了解疾病进展和对治疗的反应。人工智能和机器学习为发现生物标志物提供了一种新的方法,利用大量数据来识别模式并优化现有的生物标志物。此外,本文还涉及到数字生物标志物的出现,它使用技术来评估个人的生理和行为状态,以及正确处理组学和多组学数据对于计算机系统有效处理的重要性。然而,本文承认人工智能/机器学习在识别生物标志物方面带来的挑战,包括数据中的潜在偏差和数据表示多样性的需求。为了应对这些挑战,本文提出了AI/ML算法开发中的监管和多样性的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.40
自引率
0.00%
发文量
165
审稿时长
7.5 months
期刊介绍: The Brazilian Journal of Pharmaceutical Sciences accepts for publication Original Papers applicable to the fields of Pharmaceutical Sciences; Reviews and Current Comment Articles, which are published under the Scientific Editor and Associate Editors invitation to recognized experts or when they are spontaneously submitted by the authors in the form of abstracts to have their importance evaluated. A critical view of the subject with insertions of results of previous works in the field in relation to the state of art must be included; Short Communications reporting new methods and previews of works on researches of outstanding importance in which originality justify a quick publication. A maximum of 2000 words excluding tables, figures and references is an acceptable limit. One table, one figure and ten references may be added, and Book Reviews of the latest editions of books, prepared by specialists invited by the Scientific Editor and Associate Editors. Thematic Supplements as well as those related to scientific meetings can be published under the Scientific Editor and/or Associate Editors agreement.
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