T. Stroykova, N. Geppe, O. Bashkina, E. Seliverstova, A. Shilova, M. Shtepo
{"title":"Phenotyping of bronchial asthma in children: challenges and ways to address them","authors":"T. Stroykova, N. Geppe, O. Bashkina, E. Seliverstova, A. Shilova, M. Shtepo","doi":"10.20953/1817-7646-2022-4-104-109","DOIUrl":null,"url":null,"abstract":"Objective. To summarize and analyze data from foreign publications on bronchial asthma phenotyping using cluster analysis. Main points: asthma in children has various factors underlying inflammation and symptom control. There are methodological approaches that can eliminate this heterogeneity, for example, cluster analysis to identify asthma phenotypes and predict treatment outcomes. However, there have been no attempts to cluster patients by the relationship between treatment and clinical outcome. The approaches to long-term prognosis in children with asthma have not been sufficiently studied. Key words: children, bronchial asthma","PeriodicalId":38157,"journal":{"name":"Voprosy Prakticheskoi Pediatrii","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Voprosy Prakticheskoi Pediatrii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.20953/1817-7646-2022-4-104-109","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Objective. To summarize and analyze data from foreign publications on bronchial asthma phenotyping using cluster analysis. Main points: asthma in children has various factors underlying inflammation and symptom control. There are methodological approaches that can eliminate this heterogeneity, for example, cluster analysis to identify asthma phenotypes and predict treatment outcomes. However, there have been no attempts to cluster patients by the relationship between treatment and clinical outcome. The approaches to long-term prognosis in children with asthma have not been sufficiently studied. Key words: children, bronchial asthma
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