Clinical observation of a patient with small and large intestine lesions with Crohn's disease and eosinophilic colitis

Abstract

Crohn's disease (granulomatous enteritis, granulomatous colitis, terminal ileitis) is a chronic relapsing disease characterized by transmural granulomatous inflammation with segmental lesions often of the small and large intestine. Eosinophilic colitis is a rare disease characterized by high level of eosinophilic infiltrate in the colon wall in patients with symptoms, more often manifested by abdominal pain or diarrhea. We face more often with the unique combination of these two diseases, characterized by different types of immunological reactions. We presented the clinical case of Crohn's disease and eosinophilic colitis in a 15-year-old boy. We face more often with the unique combination of these two pathological conditions, characterized by different types of immunological reactions, The article presents the clinical case of Crohn's disease and eosinophilic colitis in a 15-year-old boy. The aim of this clinical case is to increase the knowledge of practitioners about inflammatory bowel diseases, to point out possible combinations of different immunological inflammatory reactions in one patient, and the difficulties in diagnosing and managing this kind of patients. Key words: Crohn's disease, eosinophilic colitis, diagnosis, treatment, hormone-resistant form, targeted therapy, children