Surgical Debridement for Acute and Chronic Osteomyelitis in Children.

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2023-03-17 eCollection Date: 2023-01-01 DOI:10.2106/JBJS.ST.21.00039
Ernest Ekunseitan, Coleen S Sabatini, Ishaan Swarup
{"title":"Surgical Debridement for Acute and Chronic Osteomyelitis in Children.","authors":"Ernest Ekunseitan, Coleen S Sabatini, Ishaan Swarup","doi":"10.2106/JBJS.ST.21.00039","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Osteomyelitis is an infection of the bone that commonly occurs in pediatric populations. First-line treatment most often involves a course of antibiotics. In recent studies, surgical debridement, in addition to antibiotics, has been shown to provide positive clinical and functional outcomes in children. Debridement is most often indicated in patients with an abscess or in those who do not respond to empiric antibiotic therapy; however, there are limited video resources describing this technique in pediatric patients.</p><p><strong>Description: </strong>The key steps of the procedure, which are demonstrated in the present video article, are (1) preoperative planning, (2) positioning, (3) subperiosteal exposure and debridement, (4) cortical window creation, (5) irrigation, (6) adjunctive treatment, (7) drain placement, (8) wound closure, (9) dressing and immobilization, and (10) wound check and drain removal.</p><p><strong>Alternatives: </strong>Nonoperative treatment is usually indicated for acute osteomyelitis in which patients present with little to no necrotic tissue or abscess formation. In these cases, a course of broad-spectrum antibiotics may be sufficient for a cure.</p><p><strong>Rationale: </strong>This procedure allows for the removal of necrotic bone and soft tissue, thus facilitating the recovery process. It also allows for the retrieval of tissue samples that may be used to guide selection of the appropriate antibiotic therapy. Surgical debridement is a safe and reliable technique that has been associated with positive long-term outcomes.</p><p><strong>Expected outcomes: </strong>We expect that some patients will require repeat surgical debridement procedures to decrease pathogen burden and prevent future complications. However, we expect that the majority of patients who undergo surgical debridement for uncomplicated osteomyelitis will recover full functionality of the affected limb with no associated long-term sequelae<sup>10</sup>.</p><p><strong>Important tips: </strong>Understand preoperative imaging to identify areas of infection, localize critical structures and the physis, and plan surgical approaches.Use extensile approaches and preserve vascularity during the approach.Perform subperiosteal dissection and create a cortical window to debride areas of infection, but avoid excessive periosteal stripping.Close the dead space and wound in a layered manner.</p><p><strong>Acronyms and abbreviations: </strong>MRI = magnetic resonance imagingK-wire = Kirschner wireMRSA = methicillin-resistant <i>Staphylococcus aureus</i>PDS = polydiaxonone.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2023-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10807896/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2106/JBJS.ST.21.00039","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0

Abstract

Background: Osteomyelitis is an infection of the bone that commonly occurs in pediatric populations. First-line treatment most often involves a course of antibiotics. In recent studies, surgical debridement, in addition to antibiotics, has been shown to provide positive clinical and functional outcomes in children. Debridement is most often indicated in patients with an abscess or in those who do not respond to empiric antibiotic therapy; however, there are limited video resources describing this technique in pediatric patients.

Description: The key steps of the procedure, which are demonstrated in the present video article, are (1) preoperative planning, (2) positioning, (3) subperiosteal exposure and debridement, (4) cortical window creation, (5) irrigation, (6) adjunctive treatment, (7) drain placement, (8) wound closure, (9) dressing and immobilization, and (10) wound check and drain removal.

Alternatives: Nonoperative treatment is usually indicated for acute osteomyelitis in which patients present with little to no necrotic tissue or abscess formation. In these cases, a course of broad-spectrum antibiotics may be sufficient for a cure.

Rationale: This procedure allows for the removal of necrotic bone and soft tissue, thus facilitating the recovery process. It also allows for the retrieval of tissue samples that may be used to guide selection of the appropriate antibiotic therapy. Surgical debridement is a safe and reliable technique that has been associated with positive long-term outcomes.

Expected outcomes: We expect that some patients will require repeat surgical debridement procedures to decrease pathogen burden and prevent future complications. However, we expect that the majority of patients who undergo surgical debridement for uncomplicated osteomyelitis will recover full functionality of the affected limb with no associated long-term sequelae10.

Important tips: Understand preoperative imaging to identify areas of infection, localize critical structures and the physis, and plan surgical approaches.Use extensile approaches and preserve vascularity during the approach.Perform subperiosteal dissection and create a cortical window to debride areas of infection, but avoid excessive periosteal stripping.Close the dead space and wound in a layered manner.

Acronyms and abbreviations: MRI = magnetic resonance imagingK-wire = Kirschner wireMRSA = methicillin-resistant Staphylococcus aureusPDS = polydiaxonone.

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
儿童急性和慢性骨髓炎的外科清创术
背景:骨髓炎是一种常见于儿童的骨感染。一线治疗通常包括一个疗程的抗生素治疗。最近的研究表明,除抗生素治疗外,手术清创也能为儿童带来积极的临床和功能治疗效果。清创术通常适用于脓肿患者或对经验性抗生素治疗无效的患者;但是,描述这种技术在儿科患者中应用的视频资源非常有限:本视频文章中演示的手术关键步骤包括:(1) 术前计划;(2) 定位;(3) 骨膜下暴露和清创;(4) 创建皮质窗;(5) 冲洗;(6) 辅助治疗;(7) 放置引流管;(8) 关闭伤口;(9) 包扎和固定;(10) 检查伤口和移除引流管:非手术治疗通常适用于急性骨髓炎,患者几乎没有坏死组织或脓肿形成。在这种情况下,一个疗程的广谱抗生素可能就足以治愈。理由:这种手术可以清除坏死的骨头和软组织,从而促进恢复过程。此外,还可以取回组织样本,用于指导选择适当的抗生素疗法。手术清创是一种安全可靠的技术,长期效果良好:我们预计,部分患者需要重复进行手术清创,以减少病原体负担并预防未来的并发症。不过,我们预计大多数接受手术清创治疗的无并发症骨髓炎患者都能完全恢复患肢功能,且不会出现相关的长期后遗症10:了解术前成像以确定感染区域、定位关键结构和椎体,并计划手术方法。使用延伸性方法,并在手术过程中保留血管。进行骨膜下剥离并创建皮质窗口以清除感染区域,但避免过度的骨膜剥离:MRI = 磁共振成像K-wire = Kirschner wireMRSA = 耐甲氧西林金黄色葡萄球菌PDS = 聚二甲酮。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
期刊最新文献
Intentions to move abroad among medical students: a cross-sectional study to investigate determinants and opinions. Analysis of Medical Rehabilitation Needs of 2023 Kahramanmaraş Earthquake Victims: Adıyaman Example. Efficacy of whole body vibration on fascicle length and joint angle in children with hemiplegic cerebral palsy. The change process questionnaire (CPQ): A psychometric validation. Psychosexual dysfunction in male patients with cannabis dependence and synthetic cannabinoid dependence.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1