A Finite Element Analysis Rupture Index (FEARI) as an Additional Tool for Abdominal Aortic Aneurysm Rupture Prediction

B. Doyle, A. Callanan, M. Walsh, P. Grace, T. McGloughlin
{"title":"A Finite Element Analysis Rupture Index (FEARI) as an Additional Tool for Abdominal Aortic Aneurysm Rupture Prediction","authors":"B. Doyle, A. Callanan, M. Walsh, P. Grace, T. McGloughlin","doi":"10.2174/1567270000906010114","DOIUrl":null,"url":null,"abstract":"Currently, abdominal aortic aneurysms (AAAs), which are a permanent dilation of the aorta, are treated surgi- cally when the maximum transverse diameter surpasses 5.5cm. AAA rupture occurs when the locally acting wall stress exceeds the locally acting wall strength. There is a need to review the current diameter-based criterion, and so it may be clinically useful to develop an additional tool to aid the surgical decision-making process. A Finite Element Analysis Rup- ture Index (FEARI) was developed. Ten patient-specific AAAs were reconstructed, and the corresponding wall stress computed. Previous experimental work on determination of ultimate tensile strengths (UTS) from AAA tissue samples was implemented in this study. By com- bining peak wall stress along with average regional UTS, a new approach to the estimation of patient-specific rupture risk has been developed. Ten cases were studied, all of which were awaiting or had previously undergone surgical AAA repair. A detailed exami- nation of these ten cases utilising the FEARI analysis suggested that there was a possibility that some of the AAAs may have been less prone to rupture than previously considered. It is proposed that FEARI, used alongside other rupture risk factors, may improve the current surgical decision-making process. The use of FEARI as an additional tool for rupture prediction may provide a useful adjunct to the diameter-based approach in surgical decision-making.","PeriodicalId":88793,"journal":{"name":"Vascular disease prevention","volume":"6 1","pages":"114-121"},"PeriodicalIF":0.0000,"publicationDate":"2009-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"57","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vascular disease prevention","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1567270000906010114","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 57

Abstract

Currently, abdominal aortic aneurysms (AAAs), which are a permanent dilation of the aorta, are treated surgi- cally when the maximum transverse diameter surpasses 5.5cm. AAA rupture occurs when the locally acting wall stress exceeds the locally acting wall strength. There is a need to review the current diameter-based criterion, and so it may be clinically useful to develop an additional tool to aid the surgical decision-making process. A Finite Element Analysis Rup- ture Index (FEARI) was developed. Ten patient-specific AAAs were reconstructed, and the corresponding wall stress computed. Previous experimental work on determination of ultimate tensile strengths (UTS) from AAA tissue samples was implemented in this study. By com- bining peak wall stress along with average regional UTS, a new approach to the estimation of patient-specific rupture risk has been developed. Ten cases were studied, all of which were awaiting or had previously undergone surgical AAA repair. A detailed exami- nation of these ten cases utilising the FEARI analysis suggested that there was a possibility that some of the AAAs may have been less prone to rupture than previously considered. It is proposed that FEARI, used alongside other rupture risk factors, may improve the current surgical decision-making process. The use of FEARI as an additional tool for rupture prediction may provide a useful adjunct to the diameter-based approach in surgical decision-making.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
有限元分析破裂指数(FEARI)作为腹主动脉瘤破裂预测的附加工具
目前,腹主动脉瘤(AAAs)是一种永久性的主动脉扩张,当最大横径超过5.5cm时,需要手术治疗。当局部作用的壁应力超过局部作用的壁强度时,发生AAA破裂。有必要回顾目前基于直径的标准,因此开发一个额外的工具来帮助手术决策过程可能在临床上有用。提出了一种有限元分析断裂指数(FEARI)。重建10例患者特异性AAAs,并计算相应的壁应力。以前的实验工作,从AAA组织样品的极限拉伸强度(UTS)的测定在本研究中执行。通过结合峰值壁应力和平均区域UTS,开发了一种新的方法来估计患者特定的破裂风险。我们研究了10例患者,他们都在等待或之前接受过手术修复AAA。利用FEARI分析对这十个病例进行的详细检查表明,一些AAAs可能比以前认为的更不容易破裂。建议FEARI与其他破裂风险因素一起使用,可以改善当前的手术决策过程。使用FEARI作为破裂预测的额外工具,可以为基于直径的手术决策方法提供有用的辅助。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
自引率
0.00%
发文量
0
期刊最新文献
Role of Endothelial Cells in Myocardial Ischemia-Reperfusion Injury. Involvement of Human Leukocyte Antigen Class II Antibody in Pathogenesis of Transfusion-Related Acute Lung Injury (TRALI): Vascular Permeability Enhancement The Utility of Vascular Dysfunction Studies in the Prediction and Prevention of Preeclampsia: A Historical Review Roles of MEK/ERK Pathway in Vascular and Renal Tubular Actions of Angiotensin II Ocular Vascular Endothelial Heterogeneity
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1