Colorectal Adenocarcinoma: A Case Report of Cutaneous Metastatic Disease

Clara Curiel-Lew, rowski, I. Krase, J. Chao
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Abstract

A 73-year-old Caucasian man presented for evaluation of a one-month history of painful, pruritic rash across his lower abdomen and lower back. Two years earlier, he was diagnosed with stage IV invasive colorectal adenocarcinoma with multiple hepatic, pulmonary, peritoneal and osseous metastases. He had previously undergone surgical excision of the primary mass in his colon, chemotherapy with multiple drug regimens and radiotherapy to his right hip. At the time of presentation in our clinic, the patient had been treated with Lonsurf®, a combination of trifluridine (a thymidine based nucleoside analogue) and tipiracil (a thymidine phosphorylase inhibitor), for one-month duration.
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结直肠癌:皮肤转移性疾病1例报告
一个73岁的白人男性提出评估一个月的历史疼痛,瘙痒性皮疹横跨他的下腹部和下背部。两年前,他被诊断为IV期侵袭性结直肠腺癌,并发多发性肝、肺、腹膜和骨转移。此前,他曾接受过结肠原发肿块的手术切除、多种药物方案的化疗和右髋关节放疗。在我们的诊所就诊时,患者已接受Lonsurf®治疗,该治疗是trifluridine(一种胸腺嘧啶核苷类似物)和tipiracil(一种胸腺嘧啶磷酸化酶抑制剂)的联合治疗,疗程为一个月。
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