Analysis of the In Vitro and In Vivo Effects of the Photodynamic Therapy on Prostate Cancer by Using News Photosensitizers, Protoporphyrin IXPolyamines Derivatives
Chloë Fidanzi-Dugas, Bertr, Liagre, G. Chemin, A. Perraud, C. Carrion, R. Granet, V. Sol, D. Léger
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引用次数: 0
Abstract
To determine potential mechanisms by which PpIX-PA (protoporphyrin IX-polyamines; PpIX is coupled with two molecules of spermidine (PpIX-dSd) or spermine (PpIX-dSm)) inhibited prostate cancer cell viability, we studied its effects on mitochondrial membrane potential because alterations in mitochondrial structure and function have been shown to play a crucial role at early stages of apoptosis
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