Acute cholecystitis managed in a rural surgical department

D. Kopelman, N. Abaya, U. Kaplan, B. Kimmel, G. Shpolyanski, O. Hatoum
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Abstract

Objectives This study aims to define the outcome over a prolonged period of an unselected cohort of patients presenting with acute cholecystitis (AC) to a 560 bed rural hospital in Israel. Design, setting and participants Retrospective case series analysed from a single referral centre between 2006 and 2015. Separated into Group 1 managed by emergent cholecystectomy, Group 2 treated with antibiotics and delayed cholecystectomy, Group 3 treated with percutaneous cholecystostomy (PC) and selected delayed cholecystectomy and Group 4 managed entirely conservatively with no subsequent cholecystectomy. Methods Assessment of complication rates: in-hospital and delayed cause-specific morbidity and mortality along with conversion rates and the risk of intraoperative stone spillage. Results Of 321 patients hospitalized for AC, there were 50 in Group 1, 68 in Group 2, 59 in Group 3 and 98 in Group 4. Group 3 were older with more comorbidities and when coming to surgery had more open conversions. Intraoperative stone spillage was more common in Groups 2 and 3. The length of hospital stay was greater for Groups 1 and 3. Of the Group 4 cases, 63.2 per cent remained asymptomatic over a median follow-up of 78 months. Of those with recurrent biliary symptoms, 58.3 per cent were ASA Grade III/IV with 25/36 late deaths 80 per cent of which were from non-biliary causes. Conclusion In the management of AC, early cholecystectomy is favoured with non-operative approaches like PC drainage or antibiotic treatment alone being reserved for frailer comorbid cases. The absolute need for subsequent cholecystectomy is not supported by this series and requires further investigation.
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急性胆囊炎在农村外科的治疗
本研究旨在确定一组未选择的急性胆囊炎(AC)患者在以色列一家拥有560张床位的农村医院的长期预后。设计、环境和参与者2006年至2015年间对单个转诊中心的回顾性病例系列进行分析。1组采用紧急胆囊切除术,2组采用抗生素联合延迟胆囊切除术,3组采用经皮胆囊造口术(PC)并选择延迟胆囊切除术,4组完全保守治疗,不进行胆囊切除术。方法评估并发症发生率:住院和延迟的病因特异性发病率和死亡率、转化率和术中结石溢出的风险。结果321例AC住院患者中,1组50例,2组68例,3组59例,4组98例。第三组患者年龄较大,合并症较多,手术时开放性转换较多。术中结石溢漏在2组和3组更为常见。第1组和第3组住院时间更长。在第4组病例中,63.2%的患者在78个月的中位随访期间仍无症状。在胆道症状复发的患者中,58.3%为ASA III/IV级,其中25/36例晚期死亡,其中80%来自非胆道原因。结论在AC的治疗中,早期胆囊切除术是可取的,对于病情较轻的合并症患者应保留非手术方式,如PC引流或单独抗生素治疗。本研究并不支持绝对需要进行胆囊切除术,需要进一步的研究。
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Australasian Medical Journal
Australasian Medical Journal MEDICINE, GENERAL & INTERNAL-
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