{"title":"Increased incidence of thyroid cancer among breast cancer survivors: an analysis of the SEER-9 database (1973–2011)","authors":"J. Kuo, J. Chabot, James A. Lee","doi":"10.2217/IJE.15.31","DOIUrl":null,"url":null,"abstract":"Aims: We sought to re-examine the incidence of thyroid cancer among breast cancer survivors by performing a population-based, cohort analysis using the SEER-9 database. Methods: We identified 704,370 breast cancer patients, 49,663 thyroid cancer patients and 1526 patients who developed thyroid cancer after breast cancer (B1T). Results: Risk for developing thyroid cancer is greatest among survivors diagnosed with breast cancer at age less than 50 years. In general, B1T patients are younger with smaller tumors, and have a greater percentage of invasive ductal carcinoma. They develop thyroid cancer at an older age, and have a greater percentage of aggressive subtypes. Conclusion: Recognition of this association between thyroid and breast cancer should prompt increased awareness in these cancer patient populations.","PeriodicalId":42691,"journal":{"name":"International Journal of Endocrine Oncology","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2016-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2217/IJE.15.31","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Endocrine Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2217/IJE.15.31","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Aims: We sought to re-examine the incidence of thyroid cancer among breast cancer survivors by performing a population-based, cohort analysis using the SEER-9 database. Methods: We identified 704,370 breast cancer patients, 49,663 thyroid cancer patients and 1526 patients who developed thyroid cancer after breast cancer (B1T). Results: Risk for developing thyroid cancer is greatest among survivors diagnosed with breast cancer at age less than 50 years. In general, B1T patients are younger with smaller tumors, and have a greater percentage of invasive ductal carcinoma. They develop thyroid cancer at an older age, and have a greater percentage of aggressive subtypes. Conclusion: Recognition of this association between thyroid and breast cancer should prompt increased awareness in these cancer patient populations.
期刊介绍：
International Journal of Endocrine Oncology is a quarterly, peer-reviewed journal that helps the clinician to keep up to date with best practice in this fast-moving field. The journal highlights significant advances in basic and translational research, and places them in context for future therapy. The journal presents the latest research findings in diagnosis and management of endocrine cancer, together with authoritative reviews, cutting-edge editorials and perspectives that highlight hot topics and controversy in the field. Independent drug evaluations assess newly approved medications and their role in clinical practice. The journal welcomes the unsolicited submission of article proposals and original research manuscripts.
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