THE COMPARISON BETWEEN DEFICIT FUNCTIONAL NEUROLOGIST WITH VON WILLEBRAND FACTOR LEVELS IN ACUTE THROMBOTIC STROKE PATIENTS

Ita Muharram Sari, M. Islam
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引用次数: 1

Abstract

Background. There are limited studies of von Willebrand factor (vWF) and thrombotic stroke, escpecially the relationship between level of vWF and functional neurological deficit. Objective. To determine the difference between functional neurological deficit; measured by the NIHSS scale with the vWF level. Methods. Design study was cross sectional, sampling by consecutive admission according to inclusion and exclusion criteria. Blood samples were taken for vWF measurement. Patients are divided into two categories, low vWF level and high vWF levels. Deficit functional neurologist was measured by NIHSS scale. Results. The results were analyzed by chi square. From 80 patients, the result compares the level of NIHSS scale. In grup with mild NIHSS and low vWF levels (50 %) higher than grup with mild NIHSS and high vWF levels (27,27 %). In other side, grup with moderate NIHSS and low vWF levels (50 %) lower than grup with moderate NIHSS and high vWF levels (72,73 %). The difference is not significant statistically (p=0.067). Conclusion. There was no difference between deficit functional neurologist measured by NIHSS scale with von Willebrand factor levels in acute thrombotic stroke patients.
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急性血栓性脑卒中患者神经功能缺损与血管性血友病因子水平的比较
背景。血管性血友病因子(vWF)与血栓性卒中的关系研究有限,特别是vWF水平与功能性神经功能缺损的关系研究较少。目标。确定功能性神经缺损的区别;用NIHSS量表测量vWF水平。方法。设计研究是横断面的,根据纳入和排除标准连续入组抽样。采集血样进行vWF测量。患者分为低vWF水平和高vWF水平两类。神经功能缺损采用NIHSS量表进行测量。结果。结果用卡方分析。对80例患者的NIHSS量表水平进行比较。轻度NIHSS和低vWF水平组(50%)高于轻度NIHSS和高vWF水平组(27.7%)。另一方面,中度NIHSS低vWF组(50%)低于中度NIHSS高vWF组(72,73 %)。差异无统计学意义(p=0.067)。结论。在急性血栓性脑卒中患者中,NIHSS量表测量的神经功能缺损与血管性血友病因子水平无显著差异。
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审稿时长
48 weeks
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