Hypoxia: from basic mechanisms to therapeutics – a meeting report on the Keystone and HypoxiaNet Symposium

K. Nolan, Carsten C. Scholz
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引用次数: 3

Abstract

In May 2015, the hypoxia research community came together at the largest meeting in this field to date, to present and discuss their most recent and mainly unpublished findings. This meeting report aims to summarize the data presented at this conference, which were broadly separated into the areas of the cellular hypoxic response, the relevance of the hypoxic response in health and disease, and the development of new therapeutics targeting the hypoxic response.
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缺氧:从基本机制到治疗方法——Keystone和HypoxiaNet研讨会会议报告
2015年5月,缺氧研究团体聚集在一起,参加了该领域迄今为止规模最大的会议,展示和讨论了他们最新的、主要未发表的发现。本会议报告旨在总结本次会议上提交的数据,这些数据大致分为细胞缺氧反应、缺氧反应在健康和疾病中的相关性以及针对缺氧反应的新疗法的发展。
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Abstract IA-015: Hypoxia-induced SETX links replication stress with the unfolded protein response Abstract PO-033: Papaverine derivative smv-32 alleviates tumor hypoxia and radiosensitizes tumors by inhibiting mitochondrial metabolism Abstract PO-034: Changes in cancer associated fibroblast subsets following angiotensin II type I receptor blocker (ARB) treatment reduces transient hypoxia and radiation resistance Abstract IA-017: Chromatin and gene transcription in hypoxia Abstract IA-016: Metabolic deregulation drives a redox vulnerability in pancreatic cancer
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