Probiotics and blood pressure: current insights

IF 1.5 Q3 PERIPHERAL VASCULAR DISEASE Integrated Blood Pressure Control Pub Date : 2016-02-25 DOI:10.2147/IBPC.S73246
Aditya Upadrasta, R. Madempudi
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引用次数: 56

Abstract

Gut microbiota play a significant role in host metabolic processes, and recent metagenomic surveys have revealed that they are involved in host immune modulation and influence host development and physiology (organ development). Initially, probiotics are identified as potential therapeutics to treat gastrointestinal disorders and to revitalize the disturbed gut ecosystem. Currently, studies are exploring the potential for expanded uses of probiotics for improving the health conditions in metabolic disorders that increase the risk of developing cardiovascular diseases such as hypertension. Further investigations are required to evaluate targeted and effective use of the wide variety of probiotic strains in various metabolic disorders to improve the overall health status of the host. This review addresses the causes of hypertension and the hypotensive effect of probiotics, with a focus on their mechanistic action.
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益生菌和血压:最新的见解
肠道微生物群在宿主代谢过程中发挥着重要作用,最近的宏基因组研究表明它们参与宿主免疫调节并影响宿主发育和生理(器官发育)。最初,益生菌被认为是治疗胃肠道疾病和恢复紊乱肠道生态系统的潜在疗法。目前,研究正在探索扩大使用益生菌的潜力,以改善代谢紊乱的健康状况,增加患心血管疾病(如高血压)的风险。需要进一步的研究来评估在各种代谢紊乱中有针对性和有效地使用各种益生菌菌株以改善宿主的整体健康状况。本文综述了高血压的原因和益生菌的降压作用,重点介绍了它们的机制作用。
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来源期刊
Integrated Blood Pressure Control
Integrated Blood Pressure Control PERIPHERAL VASCULAR DISEASE-
CiteScore
4.60
自引率
0.00%
发文量
13
审稿时长
16 weeks
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