Effects of Ramadan fasting on oxidative stress and prooxidant-antioxidant balance: A Short Communication

Saedeh Delpazir, A. Norouzy, M. Mazidi, P. Rezaie, M. Moshiri, L. Etemad, M. Nematy, N. Vahdati
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引用次数: 3

Abstract

Aim: we conducted this study to investigate the role of Ramadan fasting on oxidative stress. Materials and method: 23 people (16 male, 7 female) aged between 25 and 65 years were recruited in this study. 10cc Venous blood samples were taken after 8- to 10- hours fasting on 2 different times: a week before Ramadan and at the end of Ramadan (day 27). Portions of the serum samples were used immediately to measure prooxidant-antioxidant balance (PAB). Results: the changes of oxidative stress was not significant in control group. Moreover, these changes also were non-significant in both gender. Oxidative stress was significantly increase in patients with CAD during Ramadan fasting. Conclusion: It seems that Ramadan fasting does not affect oxidative and prooxidant-antioxidant balance meaningfully. However, more studies are required in this field.
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斋月禁食对氧化应激和促氧化-抗氧化平衡的影响:简短的交流
目的:本研究旨在探讨斋月禁食对氧化应激的作用。材料与方法:本研究共招募年龄在25 ~ 65岁之间的23人,其中男性16人,女性7人。在斋月前一周和斋月结束(第27天)2次禁食8至10小时后采集10cc静脉血样本。部分血清样品立即用于测定促氧化-抗氧化平衡(PAB)。结果:对照组大鼠氧化应激无明显变化。此外,这些变化在两性中也不显著。在斋月禁食期间,冠心病患者的氧化应激显著增加。结论:斋月禁食似乎对氧化和促氧化-抗氧化平衡没有明显影响。然而,这一领域还需要更多的研究。
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