Fasting and apoptosis: a mini review

M. Derakhshan, R. Derakhshan
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引用次数: 3

Abstract

Fasting, that is usually described as abstinence from all food and drink for a period of time, has been experienced for ages. Health, protest, religious expressions of devotion and purification are the most important reasons for fasting. Many changes occur in the body during fasting including metabolic, mineral, hormonal, immunological and psychological. Its use as one of the oldest therapies among human populations has been recognized. Also its effects on many abnormalities for medical and therapeutic purposes have been investigated in animals and human. Recently studies have considered its role in apoptosis (or programmed cell death), and subsequently its outcome on the cell processes. Apoptosis is a dynamic process that occurs in multicellular organisms and is described by changes in many cellular processes, and biochemical alterations that lead to morphological cell changes, self-destruction and cell death. It also limits the accumulation of tumor cells. In this mini-review article the relationship between fasting and apoptosis has been summarized.
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禁食和细胞凋亡:一个小回顾
禁食,通常被描述为在一段时间内不吃任何食物和饮料,已经经历了很长时间。健康、抗议、虔诚和净化的宗教表达是斋戒的最重要原因。在禁食期间,身体会发生许多变化,包括代谢、矿物质、激素、免疫和心理。它作为人类最古老的治疗方法之一已经得到认可。此外,它对医学和治疗目的的许多异常的影响已在动物和人类中进行了研究。最近的研究考虑了它在细胞凋亡(或细胞程序性死亡)中的作用,以及随后对细胞过程的影响。细胞凋亡是发生在多细胞生物中的一个动态过程,它是由许多细胞过程的变化和导致细胞形态变化、自我毁灭和细胞死亡的生化改变所描述的。它也限制了肿瘤细胞的积累。本文综述了禁食与细胞凋亡的关系。
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