{"title":"Determination amount of silymarin and pharmaceutical products from milk thistle waste obtained from cold press","authors":"Derya Duran, S. Ötleş, E. Karasulu","doi":"10.23893/1307-2080.aps.05706","DOIUrl":null,"url":null,"abstract":"Silybum marianum (L.) Gaertn (synonym Carduus marianus L.) is known as milk thistle. It belongs to Asteraceae family. It originates from the Mediterranean area. However, it has spread to other countries in Europe, Asia, Australia and both Americas1. The primary content of S. marianum is the presence of a group of flavonolignans known as silymarin in the pericarp and seed coat 2. The rate of flavonolignans is usually between 1.5% and 3.5% of the fruit weight1. Silymarin consists of silybin, isosilybin, silydianin, silychristin, isosilychrystin and isosilybinin1.3. Since among flavonolignan compounds silybin has detoxificationing ABSTRACT","PeriodicalId":6962,"journal":{"name":"ACTA Pharmaceutica Sciencia","volume":"1 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACTA Pharmaceutica Sciencia","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23893/1307-2080.aps.05706","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Pharmacology, Toxicology and Pharmaceutics","Score":null,"Total":0}
引用次数: 4
Abstract
Silybum marianum (L.) Gaertn (synonym Carduus marianus L.) is known as milk thistle. It belongs to Asteraceae family. It originates from the Mediterranean area. However, it has spread to other countries in Europe, Asia, Australia and both Americas1. The primary content of S. marianum is the presence of a group of flavonolignans known as silymarin in the pericarp and seed coat 2. The rate of flavonolignans is usually between 1.5% and 3.5% of the fruit weight1. Silymarin consists of silybin, isosilybin, silydianin, silychristin, isosilychrystin and isosilybinin1.3. Since among flavonolignan compounds silybin has detoxificationing ABSTRACT
期刊介绍：
Acta Pharmaceutica Sciencia (Acta Pharm. Sci.), formerly known as Bulletin of Pharmacy and Acta Pharmaceutica Turcica is a peer-reviewed scientific journal publishing current research and reviews covering all fields of pharmaceutical sciences since 1953. The original studies accepted for publication must be unpublished work and should contain data that have not been published elsewhere as a whole or a part. The reviews must provide critical evaluation of the state of knowledge related with the subject. All manuscripts has to be written in clear and concise English. Starting from 2016, the journal will be issued quarterly both in paper and on-line formates also publish special issues for national or international scientific meetings and activities in the coverage field.
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