{"title":"Optimal control and global stability of the SEIQRS epidemic model","authors":"M. Azoua, A. Azouani, I. Hafidi","doi":"10.28919/cmbn/7880","DOIUrl":null,"url":null,"abstract":". Medical treatment, vaccination, and quarantine are the most efficacious controls in preventing the spread of contagious epidemics such as COVID-19. In this paper, we demonstrate the global stability of the endemic and disease-free equilibrium by using the Lyapunov function. Moreover, we apply the three measures to minimize the density of infected people and also reduce the cost of controls. Furthermore, we use the Pontryagin Minimum Principle in order to characterize the optimal controls. Finally, we execute some numerical simulations to approve and verify our theoretical results using the fourth order Runge-Kutta approximation through Matlab","PeriodicalId":44079,"journal":{"name":"Communications in Mathematical Biology and Neuroscience","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Communications in Mathematical Biology and Neuroscience","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.28919/cmbn/7880","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"COMPUTER SCIENCE, INFORMATION SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
. Medical treatment, vaccination, and quarantine are the most efficacious controls in preventing the spread of contagious epidemics such as COVID-19. In this paper, we demonstrate the global stability of the endemic and disease-free equilibrium by using the Lyapunov function. Moreover, we apply the three measures to minimize the density of infected people and also reduce the cost of controls. Furthermore, we use the Pontryagin Minimum Principle in order to characterize the optimal controls. Finally, we execute some numerical simulations to approve and verify our theoretical results using the fourth order Runge-Kutta approximation through Matlab
期刊介绍:
Communications in Mathematical Biology and Neuroscience (CMBN) is a peer-reviewed open access international journal, which is aimed to provide a publication forum for important research in all aspects of mathematical biology and neuroscience. This journal will accept high quality articles containing original research results and survey articles of exceptional merit.