Development of pulmonary atelectasis after experimental radiation exposure

Abstract

Results . Atelectasis occurred at the early stages of the experiment is surfactant-dependent, which is confirmed by the decreased amount of PS and PL in lavage fluid. The formation of atelectasis in later periods is caused by the obturation, narrowing of the lumen of the bronchi and bronchioles due to thickening of the epithelial lining and pronounced bronchial bronchoconstriction. Conclusion. Understanding the mechanisms of development of atelectasis is necessary in order to prevent the pathology described above and reduce the risk of complications.