Meiosis Remodeled: Inclusion of New Parts to Poppit Bead Models Enhances Understanding of Meiosis
J. LaFountain, G. K. Rickards
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引用次数: 1
Abstract
A long-standing tradition uses strings of poppit beads of different colors to model meiosis, especially to show how segments of paired homologous chromosomes are recombined. Our use of orthodontic latex bands to model cohesion of sister chromatids, and plastic coffee stirrers as microtubules, extends what can normally be achieved with ‘standard’ commercial kits of beads, so emphasizing the importance of four key elements of meiosis: (a) the role of chromosome replication before meiosis itself begins; (b) pairing and exchange (chiasma formation) of homologous chromosomes during meiosis I; (c) centromere (kinetochore) attachment and orientation within/on the spindle during meiosis I and meiosis II; and (d) the differential loss of arm and centromere cohesion at onset of anaphase I and anaphase II. These are essential elements of meiosis that students best need to visualize, not just read and think about. Bead modeling leads them in that direction, as our gallery of figures and accompanying text show. Citation: LaFountain JR, Rickards GK. 2022. Meiosis remodeled: Inclusion of new parts to Poppit Bead models enhances understanding of meiosis. CourseSource. https://doi.org/10.24918/ cs.2022.2 Editor: Leocadia Paliulis, Bucknell University Received: 3/24/2021; Accepted: 10/7/2021; Published: 2/3/2022 Copyright: © 2022 LaFountain and Rickards. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. The authors affirm that they own the copyright to all figures and drawings and written text, except for figures in supporting material entitled ‘Meiosis Survey’ where questions 25 – 30 contain drawings from a textbook, for which the authors have obtained permission and annotated on the drawings with this statement: ‘From CUMMINGS. Instructor’s edition for Cummings’ Human Heredity: Principles and Issues, Tenth Edition.' © 2014 Brooks/Cole, a part of Cengage, Inc. Reproduced by permission. www.cengage.com/permissions Conflict of Interest and Funding Statement: Neither of the authors has a financial, personal, or professional conflict of interest related to this work Supporting Materials: Supporting File S1. Meiosis remodeled – Meiosis survey PowerPoint slides *Correspondence to: James R. LaFountain Jr. 657 Cooke Hall, University at Buffalo North Campus, Buffalo, NY 14260. Email: jrl@buffalo.edu. Telephone: (716) 645-4965. Fax: (716) 645-2975 CourseSource | www.coursesource.org 2022 | Volume 09 1 Lesson
减数分裂重塑:将新部分加入到核珠模型中增强了对减数分裂的理解
一个长期存在的传统是用不同颜色的罂粟珠串来模拟减数分裂,特别是用来显示成对的同源染色体片段是如何重组的。我们使用正畸乳胶带来模拟姐妹染色单体的凝聚力,并使用塑料咖啡搅拌器作为微管,扩展了通常使用“标准”商业珠粒套件可以实现的功能,因此强调了减数分裂的四个关键要素的重要性:(a)染色体复制的作用在减数分裂开始之前;(b)减数分裂I期间同源染色体的配对交换(交叉形成);(c)减数分裂I和减数分裂II期间着丝粒(着丝点)在纺锤体内/上的附着和定向;(d)在后期I和后期II开始时臂和着丝粒内聚的差异丧失。这些都是减数分裂的基本要素,学生们最好把它们形象化,而不仅仅是阅读和思考。头部建模引导他们朝这个方向发展,正如我们的图库和随附的文本所示。来源:LaFountain JR, Rickards GK。2022. 减数分裂重塑:将新部分纳入Poppit珠模型增强了对减数分裂的理解。CourseSource。https://doi.org/10.24918/ cs.2022.2编辑:Leocadia Paliulis, Bucknell University收稿日期:3/24/2021;接受:10/7/2021;出版日期:2/3/2022版权所有:©2022 LaFountain and Rickards。这是一篇在知识共享署名-非商业-相同方式共享4.0国际许可协议下发布的开放获取文章,该协议允许在任何媒体上不受限制的非商业使用、分发和复制,前提是要注明原作者和来源。作者确认他们拥有所有图表和文字的版权,除了标题为“减数分裂调查”的辅助材料中的图表,其中问题25 - 30包含来自教科书的图纸,作者已获得许可并在图纸上注释了以下声明:“来自CUMMINGS。”卡明斯《人类遗传:原则与问题》第十版讲师版。©2014 Brooks/Cole, Cengage, Inc.的一部分。经许可转载。www.cengage.com/permissions利益冲突和资金声明:两位作者都没有与本研究相关的财务、个人或专业利益冲突。减数分裂重塑-减数分裂调查幻灯片*通讯:James R. LaFountain Jr. 657 Cooke Hall, University at Buffalo North Campus, Buffalo, NY 14260。电子邮件:jrl@buffalo.edu。电话:(716)645-4965。传真:(716)645-2975 CourseSource | www.coursesource.org 2022 |卷09 1课
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