How can health systems be strengthened to control and prevent an Ebola outbreak? A narrative review.

Q1 Environmental Science Infection Ecology and Epidemiology Pub Date : 2015-11-24 eCollection Date: 2015-01-01 DOI:10.3402/iee.v5.28877
Krishna Regmi, Ruth Gilbert, Colin Thunhurst
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Abstract

The emergence and re-emergence of infectious diseases are now more than ever considered threats to public health systems. There have been over 20 outbreaks of Ebola in the past 40 years. Only recently, the World Health Organization has declared a public health emergency of international concern (PHEIC) in West Africa, with a projected estimate of 1.2 million deaths expected in the next 6 months. Ebola virus is a highly virulent pathogen, often fatal in humans and non-human primates. Ebola is now a great priority for global health security and often becomes fatal if left untreated. This study employed a narrative review. Three major databases - MEDLINE, EMBASE, and Global Health - were searched using both 'text-words' and 'thesaurus terms'. Evidence shows that low- and middle-income countries (LMICs) are not coping well with the current challenges of Ebola, not only because they have poor and fragile systems but also because there are poor infectious disease surveillance and response systems in place. The identification of potential cases is problematic, particularly in the aspects of contact tracing, infection control, and prevention, prior to the diagnosis of the case. This review therefore aims to examine whether LMICs' health systems would be able to control and manage Ebola in future and identifies two key elements of health systems strengthening that are needed to ensure the robustness of the health system to respond effectively.

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如何加强卫生系统以控制和预防埃博拉疫情爆发?叙述性综述。
现在,传染病的出现和再次出现比以往任何时候都更被视为对公共卫生系统的威胁。在过去 40 年里,埃博拉疫情爆发了 20 多次。就在最近,世界卫生组织宣布西非进入国际关注的公共卫生紧急状态(PHEIC),预计未来 6 个月内将有 120 万人死亡。埃博拉病毒是一种毒性极强的病原体,人类和非人灵长类动物感染后往往会死亡。埃博拉病毒目前是全球卫生安全的重中之重,如果不及时治疗,往往会致命。本研究采用了叙述性综述的方法。使用 "文本词 "和 "词库词 "检索了三个主要数据库:MEDLINE、EMBASE 和 Global Health。有证据表明,中低收入国家(LMICs)并不能很好地应对当前埃博拉病毒带来的挑战,这不仅是因为这些国家的系统不完善且脆弱,还因为它们的传染病监测和应对系统不完善。在确诊病例之前,潜在病例的识别存在问题,尤其是在接触者追踪、感染控制和预防方面。因此,本综述旨在研究低收入与中等收入国家的卫生系统是否有能力在未来控制和管理埃博拉病毒,并确定了加强卫生系统所需的两个关键要素,以确保卫生系统的稳健性,从而有效应对埃博拉病毒。
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来源期刊
Infection Ecology and Epidemiology
Infection Ecology and Epidemiology Environmental Science-Environmental Science (miscellaneous)
CiteScore
8.70
自引率
0.00%
发文量
4
审稿时长
12 weeks
期刊介绍: Infection Ecology & Epidemiology aims to stimulate inter-disciplinary collaborations dealing with a range of subjects, from the plethora of zoonotic infections in humans, over diseases with implication in wildlife ecology, to advanced virology and bacteriology. The journal specifically welcomes papers from studies where researchers from multiple medical and ecological disciplines are collaborating so as to increase our knowledge of the emergence, spread and effect of new and re-emerged infectious diseases in humans, domestic animals and wildlife. Main areas of interest include, but are not limited to: 1.Zoonotic microbioorganisms 2.Vector borne infections 3.Gastrointestinal pathogens 4.Antimicrobial resistance 5.Zoonotic microbioorganisms in changing environment
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