Relationship Between Xanthine Oxidoreductase Activity and BRCA1 Levels in Patients with Stage IIIA and IIIB Non-Small Cell Lung Cancer Being Treated with Neoadjuvant Chemotherapy

S. Yalçın, A. Sezer, A. Sümbül, Samet Rahatli, Ö. Altundağ, A. M. Sedef, O. Ozyılkan
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引用次数: 0

Abstract

Many biomarkers have emerged as prognostic and predictive markers for NSCLC. Among them, the common biomarkers are the epidermal growth factor receptor (EGFR), 5 endonuclease enzyme of nucleotide excision repair (ERCC1), Kirsten sarcoma virus, which is a proto-oncogene (K-ras), and regulator subunit of ribonucleotide reductase. Besides, there is huge evidence suggesting that there might be a prognosis between NSCLC and BRCA1, XOR.1-3
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接受新辅助化疗的IIIA期和IIIB期非小细胞肺癌患者黄嘌呤氧化还原酶活性与BRCA1水平的关系
许多生物标志物已成为非小细胞肺癌的预后和预测标志物。其中,常见的生物标志物有表皮生长因子受体(EGFR)、核苷酸切除修复5内切酶(ERCC1)、原癌基因Kirsten肉瘤病毒(K-ras)、核糖核苷酸还原酶调节亚基。此外,大量证据表明,NSCLC与BRCA1、xor之间可能存在预后差异
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来源期刊
CiteScore
0.10
自引率
0.00%
发文量
16
审稿时长
29 weeks
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