Radiotherapy-Related Dural Sarcoma and Its Management: Case Report

Abstract

Sarcomas are malignant neoplasms that arise from mesenchymal tissues. Sarcomas are a rare type of solid cancers, encompassing more than one hundred subtypes, and occur at any age.1 Sarcomas of the meninges may originate primarily from mesenchymal cells or may be metastases of extracranial soft tissue sarcomas.2 Symptoms such as nausea, vomiting, headache, seizure, and spinal cord compression may occur depending on the size and location of the tumor. Cranial magnetic resonance imaging (MRI) is often used for diagnosis. The primary treatment for sarcomas is surgery; other treatment options include radiotherapy (RT), chemotherapy (CT), targeted therapies, and immunotherapy.3 Though RT is one of the risk factors for sarcoma development, RT-related dural sarcomas are extremely rare.2 There is no consensus on the management of these extremely rare, malignant neoplasms. Here, the authors report a case of RT-related dural sarcoma and its management.