L. Demir, Duygu Bayır, Ruhengiz Özdoğan, B. Yıldız, M. Dinçer
{"title":"A Real-World Comparison of Pazopanib Versus Sunitinib in Metastatic Renal Cell Carcinoma: Focus on Poor-Risk patients, A Single-Center Study","authors":"L. Demir, Duygu Bayır, Ruhengiz Özdoğan, B. Yıldız, M. Dinçer","doi":"10.37047/jos.2020-76764","DOIUrl":null,"url":null,"abstract":"The Memorial Sloan Kettering Cancer Center (MSKCC) and International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) have classified RCC according to clinical characteristics into three risk groups: favorable, intermediate, and poor. Previous reports have demonstrated that patients with poor-risk features (according to MSKCC criteria and neutrophil and platelet counts) presented a significantly shorter overall survival (OS) than patients with favorableto intermediate-risk features, and the twoyear survival rate of poor-risk patients did not exceed 7%, while that of the favorableto intermediate-risk patients was 53-75%.4,5","PeriodicalId":31838,"journal":{"name":"Journal of Oncological Sciences","volume":"6 1","pages":"153-163"},"PeriodicalIF":0.0000,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Oncological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.37047/jos.2020-76764","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
The Memorial Sloan Kettering Cancer Center (MSKCC) and International Metastatic Renal Cell Carcinoma Database Consortium (IMDC) have classified RCC according to clinical characteristics into three risk groups: favorable, intermediate, and poor. Previous reports have demonstrated that patients with poor-risk features (according to MSKCC criteria and neutrophil and platelet counts) presented a significantly shorter overall survival (OS) than patients with favorableto intermediate-risk features, and the twoyear survival rate of poor-risk patients did not exceed 7%, while that of the favorableto intermediate-risk patients was 53-75%.4,5