Hand,foot and mouth disease in Yangpu District of Shanghai:an analysis of epidemiologic characteristics in 2009-2013

Abstract

Objective To analyze the etiological and epidemiological characteristics of hand,foot and mouth disease(HFMD)in Yangpu District of Shanghai from 2009 to 2013,providing evidence for its prevention and control.Methods HFMD surveillance and report were done using the National Disease Supervision Information Management System.Descriptive epidemiological method was used to analyze the 2009-2013 epidemiologic characters and etiological characters(partial patients)of HFMD in Yangpu District,Shanghai.Nucleic acid of enterovirus(EV)genome was detected by real-time PCR in some patients.Results A total of 4 974 cases of HFMD were reported during 2009-2013 in Yangpu District,Shanghai,with the average annual incidence rate of 755.3per million,with no death cases and 9(0.18%)severe cases.The peak incidence was observed in the period of April to July.The epidemic peak had an increasing tendency and could be delayed.The incidence rates of HFMD were increased at an annual basis(Ptrend0.05)in all communities and were significantly different between different communities(P0.05).Most of the cases were less than 5-year-old scattered and childcare children.The main epidemic strains were EV71 and Cox A16 in 2010,and other enterovirus and Cox A16 in 2011-2013.The proportions of other enterovirus strains were increased,with overlapping phenomenon found in the pathogenic spectrum curves before and after the epidemic peak.Conclusion The 2009-2013 epidemiology of HFMD in Yangpu District of Shanghai had prominent seasonal,regional and population characteristics.Epidemic superiority strains vary annually and influence the epidemic trend and severity.