Endovascular treatment for basilar tip aneurysms associated with moyamoya disease

Yan Chen, Dai Dongwei, Yibin Fang, Qinghai Huang, Wen-yuan Zhao, Jianmin Liu
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Abstract

Objective To assess the safety and efficacy of endovascular treatment for basilar tip aneurysms associated with moyamoya disease.Methods Seven patients with basilar tip aneurysms associated with moyamoya disease were treated by endovascular embolization in our department between Oct.2006 and Jul.2013.Two patients were treated by pure coiling and the others were treated by stent-assisted coiling.The immediate angiographic result was evaluated by Raymond scale.Postoperative angiographic and clinical follow-ups were obtained in all the 7cases,and the clinical outcomes were evaluated by the modified Rankin score(mRS).Results All the 7 patients successfully received endovascular embolization without procedure-related complications.Immediate angiographic results showed complete occlusion in 3cases,neck residual in 2,and partial occlusion in 2.Postoperative angiographic follow-ups were obtained for a mean of(10.4±3.5)months,with complete occlusion found in 6patients and stable in 1patient.No progressive thrombosis or in-stent occlusion were detected by follow-up angiograms in the stent group.Clinical follow-ups were obtained for a mean of(21.1±15.8)months and all the patients reported good outcomes(mRS 0-2).Conclusion Our data suggest that endovascular embolization is a safe and efficient treatment for basilar tip aneurysms associated with moyamoya disease.Stent-assistance might be a safe and effective option for the large or wide-necked aneurysms,though the long-term safety still remains to be confirmed.
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烟雾病相关基底尖动脉瘤的血管内治疗
目的评价血管内治疗基底尖动脉瘤合并烟雾病的安全性和有效性。方法对我科2006年10月至2013年7月收治的7例基底尖动脉瘤合并烟雾病患者行血管内栓塞治疗。2例患者采用单纯盘绕治疗,其余患者采用支架辅助盘绕治疗。即刻血管造影结果采用雷蒙德评分法评价。7例患者均行术后血管造影及临床随访,采用改良Rankin评分(mRS)评价临床疗效。结果7例患者均成功行血管内栓塞,无手术并发症。即时血管造影结果显示完全闭塞3例,颈部残留2例,部分闭塞2例。术后血管造影随访平均为(10.4±3.5)个月,6例患者发现完全闭塞,1例患者病情稳定。支架组随访血管造影未发现进展性血栓形成或支架内闭塞。临床随访时间平均为(21.1±15.8)个月,全部患者预后良好(mRS 0-2)。结论血管内栓塞是治疗基底尖动脉瘤合并烟雾病的一种安全有效的方法。对于大的或宽颈的动脉瘤,支架辅助可能是一种安全有效的选择,尽管长期的安全性仍有待证实。
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来源期刊
第二军医大学学报
第二军医大学学报 Medicine-Medicine (all)
CiteScore
0.50
自引率
0.00%
发文量
14752
期刊介绍: Founded in 1980, Academic Journal of Second Military Medical University(AJSMMU) is sponsored by Second Military Medical University, a well-known medical university in China. AJSMMU is a peer-reviewed biomedical journal,published in Chinese with English abstracts.The journal aims to showcase outstanding research articles from all areas of biology and medicine,including basic medicine(such as biochemistry, microbiology, molecular biology, genetics, etc.),clinical medicine,public health and epidemiology, military medicine,pharmacology and Traditional Chinese Medicine),to publish significant case report, and to provide both perspectives on personal experiences in medicine and reviews of the current state of biology and medicine.
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