INVESTIGATION ON ASSOCIATION OF SERUM BILIRUBIN CONCENTRATION WITH RISK OF CORONARY HEART DISEASE

Zhang Shu-ya, Chen Hong-tao
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Abstract

Objective To investigate the relationship between of serum bilirubin concentrations and risk of coronary heart drsease (CHD). Methods Serum bilirubin concentrations were determined in 12 cases with acute myocardial infarction(AMI)、37 cases with unstable angina pectoris (UAP) and 30 cases with UAP with arrhythmia. Results The serum total bilirubin(TB)、direct bilirubin(DB)、indirect bilirubin(IB) concentrations were lower in the three study groups of CHD than in the controls. There was significant difference between the patients with CHD and the controls. However, there was no significant difference among the three study groups of CHD. Conclusion Serum bilirubin concentrations was inversely and statistically significantly related to risk of CHD.
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血清胆红素浓度与冠心病危险关系的研究
目的探讨血清胆红素水平与冠心病发病风险的关系。方法对12例急性心肌梗死(AMI)患者、37例不稳定型心绞痛(UAP)患者和30例合并心律失常的UAP患者进行血清胆红素测定。结果3组冠心病患者血清总胆红素(TB)、直接胆红素(DB)、间接胆红素(IB)浓度均低于对照组。冠心病患者与对照组有显著性差异。而冠心病三个研究组间无显著性差异。结论血清胆红素浓度与冠心病发生风险呈负相关,且有统计学意义。
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