The Role of Matrix Metalloproteinases in Human Body

H. Hasanov, K. Mammadova, F. Guliyeva, U. Azizova, N. Mikailova
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引用次数: 3

Abstract

MMPs are Zn dependent proteases. All of MMPs kind is multi-domain proteins and their activities are regulated by tissue inhibitors of metalloproteinases. The prevention of the pathologies which is created by MMPs used some synthetic and naturally inhibitors. This review will explain the attitude MMPs and some chemical and physical factors which to being high level and low could affect to MMPs activity and synthesis as caffeine, one of snake venom components, melatonin, serotonin, stress factor, E and C vitamins.
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基质金属蛋白酶在人体中的作用
MMPs是锌依赖性蛋白酶。MMPs均为多结构域蛋白,其活性受金属蛋白酶组织抑制剂的调控。预防由MMPs产生的病理使用一些合成和天然抑制剂。本文综述了影响MMPs活性和合成的化学和物理因素,如咖啡因、蛇毒成分之一、褪黑素、血清素、应激因子、维生素E和维生素C等。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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