Fluid Therapy (FT) Complications: Volumetric Overload (VO) in the patho-Aetiology of VO Shocks (VOS) and the Acute Respiratory Distress Syndrome (ARDS)

A. Ghanem
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Abstract

Fluid therapy (FT) was introduced during WW2. Ever since its complications have been frequently reported but notably some serious complications have been overlooked. The role of volumetric overload (VO) in inducing VU shocks (VOS) and causing the acute respiratory distress syndrome (ARDS) has remained overlooked, unrecognized, and underestimated till recently. The role of FT complications in inducing VOS and causing ARDS is hard to detect because VOS is a shock that complicates another existing shock seamlessly and un-noticed. The author attributes this to the faulty rules on FT dictated by the wrong Starling’s law that causes many errors and misconceptions of FT which mislead physicians into giving too much fluid during shock resuscitation. The research findings on the wrong Starling’s law and how it has been corrected based on the hydrodynamic of the porous orifice (G) tube and the newly recognized VOS and the new patho-aetiology and therapy of ARDS are summarized here. Other authors in support of this contention are quoted. The errors on current FT and its corrections are given. Finally, a new prospective cohort study on FT and ARDS is recommended and a call for new guidelines on FT is urgently needed.
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液体治疗(FT)并发症:容量过载(VO)在VO休克(VOS)和急性呼吸窘迫综合征(ARDS)的病理病因学中的作用
液体疗法(FT)在二战期间被引入。自那时以来,其并发症已被频繁报道,但值得注意的是,一些严重的并发症被忽视了。容量过载(VO)在诱发VU冲击(VOS)和引起急性呼吸窘迫综合征(ARDS)中的作用一直被忽视、未被认识和低估。FT并发症在诱发VOS和引起ARDS中的作用很难发现,因为VOS是一种无缝且不被注意的使另一种现有休克复杂化的休克。作者将此归因于错误的斯塔林定律(Starling’s law)对金融时报的错误规定,这导致了许多错误和对金融时报的误解,误导医生在休克复苏期间给予过多的液体。本文从G管的流体力学和新认识的VOS以及ARDS的新病理病因和治疗方法等方面综述了有关Starling定律错误的研究成果及其纠正方法。引用了支持这一论点的其他作者。给出了当前傅立叶变换的误差及其修正。最后,我们建议对FT和ARDS进行一项新的前瞻性队列研究,并迫切需要制定新的FT指南。
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