SARS-COV-2/COVID19 Induce Kawasaki-Like Disease in Children Experience of Republic of Moldova: A Report of Five Cases

N. Revenco
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Abstract

Infection with SARS-CoV-2 virus is a serious challenge for the entire medical and scientific community. Medical institutions are facing record numbers of patients and conflicting claims about SARS-CoV-2 and due to its mutagenic properties, thanks to the D614G protein from Coronavirus (CoV) defining the determines the mutagenicity of SARS - CoV and MERS-CoV [1,2]. With the expansion of the COVID-19 Pandemic, researchers have reported [3] clinical cases of multisystemic inflammatory syndrome in children (MIS-C), similar to Kawasaki disease (KD). Due to the absence of a diagnostic marker for KD, the latter is established according to the criteria of the American Society of Cardiology, in this situation with associated SARS-CoV-2 infection. We deem it appropriate to report five clinical cases of KD that met the criteria for defining an MIS-C case as defined by WHO.
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SARS-COV-2/ covid - 19在摩尔多瓦共和国儿童中诱发川崎样病的经验:附5例报告
感染SARS-CoV-2病毒是整个医学界和科学界面临的严峻挑战。由于冠状病毒(CoV)中的D614G蛋白定义了SARS-CoV和MERS-CoV的致突变性,医疗机构正面临着创纪录的患者数量和关于SARS-CoV-2的相互矛盾的说法,并且由于其致突变性[1,2]。随着COVID-19大流行的扩大,研究人员报告了100例儿童多系统炎症综合征(MIS-C)临床病例,类似于川崎病(KD)。由于缺乏KD的诊断标志物,后者是根据美国心脏病学会的标准建立的,在这种情况下伴有SARS-CoV-2感染。我们认为报告符合世卫组织定义的misc病例标准的5例临床KD病例是合适的。
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