IgG4-related sclerosing mesenteritis and its possible relation to papillarythyroid carcinoma in a 27-year-old Egyptian woman.

Abstract

Sclerosing mesenteritis (SM) is a rare fibro inflammatory disease unknown etiology involves the small bowel mesentry, most frequently observed in middle aged and older men. Recently, it was reported to be closely related to IgG4-RD. Many articles reported a close relation between IgG4-related and thyroid diseases including Hadhimoto's thyroiditis and papillary thyroid cancer. This report describes a lady with sclerosing mesenteritis (SM) proved serologically as well as histo-pathologically to be associated with IgG4-RD, with a past history of Hashimoto’s thyroiditis then a hemithyroidectomy was done to the patient for multi nodular goiter whose pathology revealed papillary adenocarcinoma and treated accordingly. These findings support the previous reports relating IgG-RD with sclerosing mesenteritis, Hashimoto’s thyroiditis and papillary thyroid carcinoma.