Cardiac metastasis of malignant melanoma: where are we standing?

T. Velho, N. Guerra, A. Nobre
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Abstract

Melanoma is the most severe neoplasm of the skin, still having a poor prognosis despite all the efforts and discoveries in the past few years. Targeted therapies improved treatment options for melanoma, bringing new hopes for patients with advanced and metastized melanoma. Currently, vemurafenib, dafrafenib, ipilimumab, pembrolizumab and trametinib are just some of the drugs approved by the United States Food and Drug Administration (FDA) for clinical use.
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恶性黑色素瘤的心脏转移:我们站在哪里?
黑色素瘤是最严重的皮肤肿瘤,尽管在过去的几年里做出了很多努力和发现,但预后仍然很差。靶向治疗改善了黑色素瘤的治疗选择,为晚期和转移性黑色素瘤患者带来了新的希望。目前,vemurafenib、dafrafenib、ipilimumab、pembrolizumab和trametinib只是美国食品和药物管理局(FDA)批准临床使用的一些药物。
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