Osteobiologics-related complexity in spine surgery: a systematic study

P. Jha
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Abstract

The aim of this systematic review was to determine the type and frequency of complications in patients who had BMP in spine fusion surgery, as well as whether there is a doseresponse relationship between BMP and complications. Because of its efficacy in supporting arthrodesis, BMP is used on-label for ALIF with LT-CAGE and off-label for various spine fusion applications in the cervical, thoracic, and lumbar spines. In a number of clinical fusion scenarios, several reports conducted over the past few years have highlighted problems associated with BMP.
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脊柱外科中骨生物学相关的复杂性:一项系统研究
本系统综述的目的是确定脊柱融合手术中BMP患者并发症的类型和频率,以及BMP与并发症之间是否存在剂量反应关系。由于BMP在支持关节融合术方面的有效性,BMP在标签上用于ALIF配合LT-CAGE,在标签外用于颈椎、胸椎和腰椎的各种脊柱融合应用。在许多临床融合案例中,过去几年进行的一些报道强调了BMP相关的问题。
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