What Comes After Immuno-Oncology Therapy for Kidney Cancer?

IF 1.1 Q4 ONCOLOGY Kidney Cancer Pub Date : 2019-01-01 DOI:10.3233/KCA-190053
H. Zahoor, V. Duddalwar, A. D'souza, A. Merseburger, D. Quinn
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引用次数: 4

Abstract

The treatment landscape of advanced renal cell carcinoma (RCC) is rapidly evolving. Immune checkpoint inhibitors (ICI) have now become the preferred first line treatment with the approval of nivolumab and ipilimumab combination in intermediate to poor risk patients. Combination/s of ICI with vascular endothelial growth factor (VEGF) inhibitors will also be approved in future. The optimal treatment of patients who progress on ICI-based therapies is not well defined as of yet. In this review, we discuss the data regarding various treatment options available in this space, their limitations, and also provide our opinion regarding treatment selection.
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肾癌免疫肿瘤治疗后会发生什么?
晚期肾细胞癌(RCC)的治疗前景正在迅速发展。随着nivolumab和ipilimumab联合应用于中低风险患者,免疫检查点抑制剂(ICI)现已成为首选的一线治疗方案。ICI联合血管内皮生长因子(VEGF)抑制剂也将在未来获得批准。目前,在基于ci的治疗中取得进展的患者的最佳治疗方法尚未得到很好的定义。在这篇综述中,我们讨论了关于这个领域的各种治疗方案的数据,它们的局限性,并提供了我们对治疗选择的意见。
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来源期刊
Kidney Cancer
Kidney Cancer Multiple-
CiteScore
0.90
自引率
8.30%
发文量
23
期刊最新文献
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