Application of the Program of Enhanced Recovery in Surgical Treatment of Patients with Colorectal Cancer Complicated by Acute Obstruction (Our Experience)

S. Na, D. Surov, I. Soloviev, A. Demko, Babkov Ov, G. V. Martynova, A. V. Sviatnenko, A. V. Osipov, B. Bezmozgin, Luk'ianiuk Pp
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Abstract

Over the last years, the number of publications devoted to the concept of enhanced recovery after surgery (ERAS) in emergency abdominal surgery application increases. The purpose of this study was a comparative analysis of the results of the ERAS-program application in surgical treatment of the patients with colorectal cancer complicated by large bowel obstruction (LBO). The study included 89 patients with obstructive colorectal carcinoma (OCRC), divided in the ERAS and control group (n=45 and n=44, respectively). During the treatment of the patients of the ERAS group in preoperative period, the following measures were taken: patient information, his psychological preparation, prevention of postoperative pain, nausea and vomiting, thromboembolic and infectious complications. Intraoperative measures included local anaesthesia of the skin in the line of laparotomy access, colon and small (under indications) intestines decompression, small intestine lavage, embryology oriented surgery and D3 lymphadenectomy, temporary installation of polyurethane catheter distal to the ligament of Treitz for early enteral nutrition, rectus sheath catheterization to carry out rectus sheath block of the anterior branches of the spinal nerves, control drainage installation into the small pelvis. In postoperative period, the early mobilization, urinary catheter and drainage removal after the patient transfer from intensive care unit were carried out. The following criteria were used as the criteria for comparative evaluation: pain syndrome intensity, need for analgesics, time of enteric deficiency arresting, postoperative complications and mortality, postoperative period duration, and patients' life quality after discharge from the hospital. It has been established that the proposed original ERAS program for this category of the patients is safe and effective due to improving the immediate results of surgical treatment.
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强化康复方案在结直肠癌合并急性梗阻手术治疗中的应用(我们的经验)
在过去的几年里,致力于提高术后恢复(ERAS)的概念在紧急腹部手术中的应用的出版物数量增加。本研究的目的是比较分析eras程序在结直肠癌合并大肠梗阻(LBO)患者手术治疗中的应用效果。本研究纳入89例梗阻性结直肠癌(OCRC)患者,分为ERAS组(n=45)和对照组(n= 44)。ERAS组患者在术前治疗过程中,采取以下措施:了解患者情况,做好患者心理准备,预防术后疼痛、恶心呕吐、血栓栓塞及感染性并发症。术中措施包括剖腹入路皮肤局部麻醉、结肠及小肠(指征下)减压、小肠灌洗、胚胎学导向手术及D3淋巴结切除术、Treitz韧带远端临时置入聚氨酯导管早期肠内营养、直肌鞘置管对脊神经前支进行直肌鞘阻滞、控制引流装置进入小骨盆。术后患者从重症监护病房转出后,进行早期活动、导尿管拔除引流。比较评价标准为:疼痛综合征强度、镇痛药需求、肠缺乏症停止时间、术后并发症及死亡率、术后持续时间、患者出院后生活质量。由于改善了手术治疗的即时效果,已经确定针对这类患者提出的原始ERAS计划是安全有效的。
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