Enzyme Function Classification

M. M. Sharif, A. Tharwat, A. Hassanien, H. Hefny
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Abstract

Enzymes are important in our life and it plays a vital role in the most biological processes in the living organisms and such as metabolic pathways. The classification of enzyme functionality from a sequence, structure data or the extracted features remains a challenging task. Traditional experiments consume more time, efforts, and cost. On the other hand, an automated classification of the enzymes saves efforts, money and time. The aim of this chapter is to cover and reviews the different approaches, which developed and conducted to classify and predict the functions of the enzyme proteins in addition to the new trends and challenges that could be considered now and in the future. The chapter addresses the main three approaches which are used in the classification the function of enzymatic proteins and illustrated the mechanism, pros, cons, and examples for each one.
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酶功能分类
酶在我们的生活中很重要,它在生物体的大多数生物过程中起着至关重要的作用,例如代谢途径。从序列、结构数据或提取的特征对酶的功能进行分类仍然是一项具有挑战性的任务。传统的实验耗费更多的时间、精力和成本。另一方面,酶的自动分类节省了精力、金钱和时间。本章的目的是涵盖和回顾不同的方法,这些方法的发展和用于分类和预测酶蛋白的功能,以及现在和未来可以考虑的新趋势和挑战。本章讨论了用于酶蛋白功能分类的主要三种方法,并说明了每种方法的机制、优点、缺点和示例。
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