Laccase Catalysis

Helina Patel, A. Gupte
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引用次数: 2

Abstract

The search for cost-effective and environmental benign practices for the production of bioactive compounds has gained considerable attention since last decade, due to increasing demand of eco-friendly processes. Many industries have started adopting routes for the development of green chemistry by employing enzymatic approaches to overcome the limitations of physico-chemical methods and environmental concerns. Laccase is one such enzyme which has gained considerable attention in recent years as a biocatalyst in organic synthesis. Laccases possess versatile biochemical properties and the reactions catalyzed by laccase require only molecular oxygen with concomitant release of water as a byproduct. They have been widely used for reactions such as dimerization, polymerization, coupling, and grafting reactions and for antibiotic modifications. This chapter summarizes the advances that have been made in developing technologies based on laccase mediated reactions in the field of medicine, agriculture, food, and pharmaceuticals.
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漆酶催化
由于对生态友好型工艺的需求不断增加,在过去十年中,寻找具有成本效益和环境友好的生产生物活性化合物的做法得到了相当大的关注。许多工业已经开始采用发展绿色化学的路线,通过使用酶的方法来克服物理化学方法的局限性和环境问题。漆酶就是其中一种近年来作为有机合成生物催化剂而受到广泛关注的酶。漆酶具有多种生化特性,由漆酶催化的反应只需要分子氧和伴随的水作为副产物的释放。它们已广泛用于二聚化、聚合、偶联和接枝反应等反应以及抗生素修饰。本章总结了基于漆酶介导反应的技术在医学、农业、食品和制药领域的发展进展。
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